QUOTE: “By all criteria of modern molecular biology, life is present
from the moment of conception.”
AUTHOR: Micheline
M. Mathews-Roth, MD is the Associate Professor of Medicine in Harvard Medical
School and an Associate Physician in Brigham and Women's Hospital. Dr.
Mathews-Roth performs basic science and clinical research in photobiology.
Her clinical studies
focus on developing photo-protective treatments for the orphan disease,
erythropoietic protoporphyria (EPP), and other human photosenstivity diseases.
She is studying beta-carotene and the amino acid cysteine as photoprotective
agents in EPP. She is also developing gene therapy methods for EPP.
Dr. Mathews-Roth has
organized the Erythropoietic
Protopophyria Research and Education Fund as a support group for EPP
patients and their families. She also acts as a consultant on the treatment of
EPP, and is on the scientific advisory board of the American Porphyria
Foundation. She is available to advise patients and their physicians about the
light-sensitive porphyrias, and the medical uses of beta-carotene and other
carotenoid pigments.
Her basic science
studies concern: 1) the molecular biology of EPP, including gene therapy
studies; 2) carotenoid molecule (as opposed to vitamin A) photoprotective and
other functions in the bacteria which contain carotenoids, as well as mammilian
cells supplemented with them; and 3) the genetics of pigment formation in the
non-photosynthetic carotenoid-containing bacteria. http://www.channing.harvard.edu/roth.htm
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